What Is Prurigo Nodularis?

Prurigo Nodularis (PN) is a rare, chronic, debilitating neuro-immune skin condition that causes skin nodules or lesions. The main hallmark of the disease is an intractable and relentless itch.

The disease burden is significant, with physical, mental, emotional and social burden on patients. There is no aspect of patients lives that the disease leaves untouched, causing significant disruption to daily life and is highly disruptive of sleep.

The symptoms are so severe that it often impacts the ability for many patients to work. This can have devastating economic implications for patients and their families.

Given that the majority of dermatologists know nothing about PN or how to treat it, the diagnosis journey is very taxing on patients time and resources.

PN In The Words Of Sufferers

“Terrible pain awake all night then sleeping all day no quality of life”

“Additional to the physical pain and discomfort, the disease impacts many other aspects of your life. It effects your confidence and your ability to interact with people in your community. The isolation impacts your mental health. It also impacts you financially with the expensive cost of medical appointments and treatments.”

“Totally debilitating”

“I had an itchy episode in front of a doctor recently. He was being dismissive and said “now what are you doing that for?” As if I had a choice . I coolly replied “I have an inflammatory skin itching disorder called PN, that’s what happens I feel intensely itchy and I scratch, if you can figure out how to stop it I’d be very grateful but otherwise I’m going to scratch. It’s a skin disease doing what it says on the tin”

“I feel so exhausted no energy”

“My family and doctors can see the sores but can not understand the pain and burning that goes on underneath the skin. Then once they erupt it’s a whole different kind of pain and itch.”